Piroxicam and Tizanidine

Piroxicam 20mg

After ditching Lyrica, I resolved to do whatever I could to stay off prescription drugs. Very rarely, I took one Skelaxin for muscle spasms. The side effects weren’t worth it most of the time, but sometimes I would be so bad off that I had to take one. As the one-year anniversary of my back and hip issues neared, I couldn’t take the daily pain and stiffness anymore. I made an appointment with the doctor who’s worked on my neck in the past. He’s smart, isn’t afraid of the latest medical technology, and perhaps most importantly, he actually spends time with his patients and listens like a human rather than a hurried robot. Unfortunately, those attributes make it very hard to get an appointment, and I waited two months despite being an established patient.

When I did finally see him, he examined my back and hip and told me a few things I already know, like I have tight muscles and joint laxity. He decided to order a lumbar MRI, which wasn’t a surprise. He also talked me into filling a couple of prescriptions because he was very worried about my high pain levels and lack of sleep. I left his office with two scripts I’d never heard of before—Piroxicam and Tizanidine.

I thought I might not fill the drugs, but pain wore me down and I headed to the pharmacy. I figured I could try them once or twice and get off them quickly if they sucked. Piroxicam is an NSAID pain reliever and Tizanidine is a short-acting muscle relaxer. I was given instructions to take the Piroxicam once per day and the Tizanidine up to three times per day. I took one of each the first night, and was asleep within an hour.

Going to sleep quickly is a big deal with a body wracked by chronic pain. Hell, going to sleep at all is monumental. When I woke up the next morning, I didn’t feel hung over at all—I just felt better. I felt genuinely rested, unlike the crappy, forced sleep that comes from some drugs.

Tizanidine 4mg
Tizanidine 4mg

For several days, I took one Piroxicam in the evening and one Tizanidine before bed, and I felt great. I hiked 21 miles one weekend, and began to feel hopeful about a mostly pain-free back, neck, and hip. As always, I follow a healthy diet and use my hot tub as much as three times per day. The good food, warm water, and new prescriptions gave me a feeling of freedom from pain, and it was priceless.

That feeling was also short-lived. After almost a week, I noticed my back pain was getting more intense again, and my neck felt badly out of alignment. This seems to be the curse with my fibromyalgia—something new helps for a little while, but before long, I’m back to hurting.

I took a break from my nightly muscle relaxer routine and didn’t notice much of a change. However, I’m now on day two of no Piroxicam, and I feel like crap. I haven’t decided yet if I’m going to start taking it again, but I’m leaning toward yes. I’m scheduled for the MRI this afternoon, and if I get stiff having to lie still for it, I’ll probably come home and pop a Piroxicam.

Have y’all tried either one of these medications? If so, what’s been your experience? I’d love to hear from you.

8 Replies to “Piroxicam and Tizanidine”

  1. i took tizanidine for a couple of years at bedtime to help combat the severe back spasms I experienced whenever I lay down. It worked very well. I no longer take them but would consider it again if needed. I have been partaking of integrative manual therapy for a number of years and no longer need the meds

    1. I’m glad you found something that works for you, Honor. I’ll have to check out integrative manual therapy. Thanks for sharing and have a great day!

  2. I use Tizanadine, it’s one of the only muscle relaxers my little body will tolerate. It works wonders on muscle tightness and spasms.

    1. Nicole, thanks for your input. I’m glad Tizanadine works for you. I’m still having decent results and definitely appreciate the lack of noticeable side effects. I hope you’re feeling well these days!

  3. ihave taking tizanidine for the past few years. My pain management doctor switch need a baclofen for a couple of months but I’m back on the tizanidine because it worked better for me. I have a lot of trouble with pain and back spasms and it’s the only thing that has helped me so far

    1. Bonnie, thanks for sharing your experience. I took Baclofen for a few months and felt like I was taking nothing. It didn’t even help a little bit. I hope you get some relief!

  4. Just started taking Piroxicam and Tizanidine. They work wonders. Getting some much needed sleep without the side effects. Linda

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